Cortical tubers are ‘disorganised’ areas of the brain that contain abnormal cells. Some people living with TSC might have one or multiple tubers, whereas others could have none.
Cortical Tubers are thought to be one of the reasons why people living with TSC develop epilepsy. No new tubers grow following birth, with tubers developing during pregnancy.
It was previously believed that the number, size and position of a person’s cortical tubers, in combination with the kind of seizures they experienced, could influence the likelihood of an individual also having learning difficulties, developmental delay and mental health problems. However, we now know that genetic changes caused by TSC can directly lead to these issues, rather than tubers and seizure type only